HYDROXPROPYLMETHYCELLULOSE HPMC

Hydroxypropyl Methylcellulose (HPMC), also known as Hypromellose, is a non-ionic, water-soluble polymer derived from natural cellulose. It is chemically modified by introducing hydroxypropyl and methyl functional groups, giving it unique properties and versatility across various industries.

Key Properties:

• Appearance: White to off-white, odorless powder or granules.
• Solubility: Soluble in cold water, forming a clear or slightly turbid solution; insoluble in hot water and most organic solvents.
• pH Range: Stable between pH 3 to 11.
• Thermal Gelation: Forms a gel when heated and dissolves upon cooling.
• Viscosity: Available in a wide range of grades, offering varying viscosities.
• Biocompatibility: Non-toxic, inert, and safe for pharmaceutical and food applications.

Applications:

1. Pharmaceutical Industry:

   • Tablet Coatings: Acts as a film-forming agent to improve appearance, control release, and protect from environmental factors.
   • Controlled-Release Formulations: Used in extended-release tablets for consistent drug delivery.
   • Excipient: Functions as a binder, stabilizer, and thickener in oral and topical formulations.

2. Construction Industry:

   • Cement and Mortar: Enhances workability, water retention, and adhesion.
   • Tile Adhesives: Improves open time and bonding strength.
   • Gypsum Products: Increases consistency and reduces cracking.

3. Food Industry:

   • Functions as a stabilizer, emulsifier, and thickener.
   • Commonly used in gluten-free products for texture improvement.
   • Found in sauces, dressings, and low-fat formulations.

4. Cosmetics and Personal Care:

   • Acts as a thickener and film-former in lotions, shampoos, and toothpaste.
   • Provides texture and stability to creams and gels.

5. Industrial Applications:

   • Paints and Coatings: Improves viscosity and stability.
   • Adhesives: Used in glues and binders for its thickening properties.

Advantages:

• Excellent water retention capabilities.
• Provides consistent performance over a wide pH range.
• Non-ionic nature ensures compatibility with various additives and active ingredients.
• Biodegradable and environmentally friendly.

Preparation and Use:

• HPMC is typically dispersed in cold water and allowed to hydrate fully to achieve the desired viscosity.
• It can be used in combination with other materials to enhance performance in specific applications.

Safety and Handling:

• Generally regarded as safe (GRAS) by regulatory agencies for pharmaceutical and food applications.
• Non-toxic and non-irritating under normal conditions of use.
• Should be stored in a cool, dry place, away from moisture.

Hydroxypropyl Methylcellulose is a versatile and essential material used in a variety of industries, valued for its adaptability, stability, and performance.